GLOBAL INITIATIVES IN PRECISION MEDICINE : COLLABORATIVE EFFORTS AND CHALLENGES

Introduction

 

 Precision medicine also known as personalized medicine is an innovative approach to tailoring disease prevention and treatment that takes into account differences in peoples genes, environment and lifestyles. Precision medicine is being used for certain types of diseases like cancer, diabetes to help know what tests and treatments are best. Doctors might use precision medicine to help them identify people who might be at high risk and help these people lower their risk. 

History

• Archibald E Gorrad is known as Father of precision medicine.

• The core approach of Sushruta, the ancient Indian physician was to offer personalised treatment by understanding a patient's unique constitution. Similarly in modern healthcare precision medicine is all about taking a personalized medication approach to treat a disease.

• President Obama announced in his 2015 State of this Union address that he is launching the precision medicine initiative a bold new research effort to revolutionize how we improve health and treat disease.

    

Initiative

To enable a new era of medicine through research, technology and policies that impower patients, researchers ,and provides to work together toward development of individualized care.The future of precision medicine will enable health care providers to tailor treatment and prevention strategies to people unique characteristics, including their genome sequence microbiome composition, health history, lifestyle  and diet. It Amis to enhance treatment effectiveness and reduce adverse effects by personalized healthcare strategies.

The proposed initiative has two main components a near term focus on concers and longer-term aim to generate knowledge application to the whole range of health and disease both components are now within our reach because of advances in basic research, including molecular biology, genomics bioinformatics. Further more the initiative taps into converging trends of increased connectivity through social media and mobile devices.

Efforts 

• Genomic Sequencing: Precision Medicine depends on analyzing on individuals DNA through techniques like genomic sequencing to identify specific genetic variations.

• Data Integration: Efforts are made to contains diverse data such as genetic, clinical, lifestyle data in order to create comprehensive profile for more accurate predictions & treatment decisions.

• Bio Marker Discovery : Efforts focus on discovering & validating biomarkers which are indicates for disease diagnosis and treatment response.

• Personalized Therapeutics: Developing treatments based on an  individuals genetic, Environmental & lifestyle factor for more effective & targeted therapies.

• Machine Learning: Utilizing AI to Analyze large datasets ,identify patterns & predict in precision medicine point.

• Patient Engagement & Education: Educating patients about the benefits & limitations of precision medicine & encouraging active participation in decision making.

Challenges

• Genomic Complexity: precision medicine faces the challenge of dealing with the intricate genomic landscape, where individual variations in the genus can have significant impacts on treatment response.

• Data Privacy: Balancing access to patient data for research while protecting individuals privacy.

• Validation of Biomarkers: Identifying reliable biomarkers for predicting treatment responses is crucial but challenging. As it extensive validation to ensure accuracy & reproducibility,

• Interdisciplinary Collaboration: precision medicine requires collaboration a many various disciplineschallenge such as genetics, information & clinical expertise which can be challenging due to different methodologies & terminologies.

• Costs: Making precision medicine affordable & accessible on a large scale.

• Ethical concerns: Addressing ethical issues related to genetic information & potential misuse.

• Regulating frameworks: Developing regulatory frameworks that balance innovation with patient safety is an ongoing challenging, especially considering the rapid advancement in precision medicine.

• Clinical trial design: Traditional clinical trial design may not be suitable for evaluating targeted therapies.

       

 Conclusion : 

         The global initiative of precision medicine stands helps for as a beacon by encouragins & developing of collaboration advancements in healthcare, fostering cross-disciplinary efforts to tailor treatment to individual patients However as we celebrate progress, its crucial to acknowledge the challenges that persist, from data sharing barriers to ethical considerations. Navigating these hurdles requires continued cooperation & innovation with a collective commitment to transparency breakthrough, we can pave the way for a future where precision medicine revolutionizes healthcare on global scale ensurity personalized & effective treatments for all.

  

Student Name:  Mehartaj. R. Maldar

Student ID: 248/122023

Qualification: B.Pharmacy

e-Mail ID: mehartajrm97@gmail.com