THE IMPORTANCE OF DIVERSITY AND INCLUSION IN CLINICAL RESEARCH & DATA MANAGEMENT

 





    

INTRODUCTION:

A clinical trial is a type of clinical research that evaluates the effects of interventions, including drugs, devices, surgeries, behavioral approaches, and lifestyle interventions.

To account for the diverse lived experiences and exposures of various populations, clinical research should be appropriately inclusive of racial and ethnic groups, as well as other populations experiencing health disparities, including sexual and gender minority populations.


WHY DIVERSITY AND INCLUSION ARE IMPORTANT IN CLINICAL RESEARCH?

It is essential to have a wide range of people from different communities participate in clinical trials to reduce biases, promote social justice and health equity, and produce more innovative science.

WHY DIVERSITY AND INCLUSION ARE IMPORTANT IN DATA MANAGEMENT?

A diverse and inclusive workforce that reflects your clients and community can have huge business benefits. As well as making work happier for everyone, DEI can help to reduce staff turnover, attract and retain key talent, and drive innovation -ultimately improving business performance.


THE IMPORTANCE OF DIVERSITY &INCLUSION IN CLINICAL RESEARCH & DATA MANAGEMENT.

 People may experience the same disease differently. It's essential that clinical trials include people with a variety of lived experiences and living conditions, as well as characteristics like race and ethnicity, age, sex, and sexual orientation so that all communities can benefit from scientific advances.

               Factors that can influence the risk and likelihood of developing a disease, experiencing a long -term health outcome, and responding to treatment include.

  • Age 

  • Biological sex

  • Life experiences

  • Unhealthy behaviors 

  • Health-promoting behaviors (adequate sleep, physical activity)

  • Unhealthy behaviors

  • Environmental conditions(access to health care or healthy foods)

  • Genetic variation and geographic ancestry

  • Underlying medical problems or presence of comorbidities(i.e..,additional disease or conditions)

Clinical trials did not always recruit participants who represented the individuals most affected by a particular disease, condition, or behavior.

Clinicians and researchers should carefully consider the inclusion or exclusion criteria for their clinical trials. For example, During the early stages of the pandemic, coronavirus disease 2019(covid-19)disproportionately affected racial and ethnic minority populations, including African American, etc. population groups, with increased cases, hospitalizations, and deaths.

It was critical that covid-19 vaccine trials included sufficient representation across population groups to better understand vaccine effectiveness in populations who vary on environmental exposures and other lived experiences.By using inclusive recruitment practices in COVID-19 clinical trials, researches have been able to show that vaccine safety and efficacy are similar across all racial and ethnic populations . Engaging diverse populations in planning and implementing such trials can also help increase public confidence that the vaccine is safe and effective.

DATA MANAGEMENT

Data management enables organizations to maintain data integrity throughout the duration of a clinical research study and ensures that a dataset is accurate, secure, reliable, and ready for analysis.

INCLUSION CRITERIA

                  1. Objective and explicit definition

                   2. Demographic,prognostic, and clinical factors 

                   3. Deductive  Approach to criteria

HOW DO YOU ENSURE DIVERSITY AND INCLUSION IN RESEARCH?

Seek and incorporate diverse perspectives 

For example: You can do this by reading the work of diverse groups, including those individuals from underrepresented groups, as you draw from multiple perspectives when formulating your research question.

IMAPCT OF DIVERSITY IN CLINICAL RESEARCH

The more diverse a group of clinical trial participants, the more we can learn about the safety and efficacy of a potential medicine or vaccine for people who have characteristics like those of the participants.

CONCLUSION:                                     

Achieving diversity in clinical trial participation is a difficult, time-consuming, and expensive exercise. This is a systematic problem and systemic requires systemic solutions. As such, we have to rethink and redesign the systemic framework for clinical trial execution to incorporate various multi-faceted approaches that will help lower the barriers and increases access for underserved communities to participate in clinical trials .when we consistently enroll representative populations in all our clinical trials, we will collectively gain a much better understanding of the safety and efficacy profiles for the drugs we develop which will benefit all patients.

REFERENCES:


Student Name: Gundrathi Sruthi

Student ID:072/042023

Qualification: B.Pharmacy

E-mail ID: sruthigunarathi@gmail.com

Comments

Post a Comment

Popular Posts